Zymeworks

RAI/II Pharmacokinetics - Multispecific Antibody Therapeutics

Multispecific Antibody Therapeutics - Vancouver, BC - Canada

Why Work for Us?

Innovation. Act with Integrity. Collaboration. Embrace Diversity. Care

We come from many countries, cultures, races, ethnicities, abilities, and nationalities. We bring our passions including singing, biking, swimming, dancing, cooking, volunteering, parenting, coaching and much more! We are proud of our nearly equal balance of men and women and strengthened by our non-binary and transgender team members. Every employee belongs.

We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.

Company Description

Zymeworks is a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation bispecific and multifunctional biotherapeutics, initially focused on the treatment of cancer. Zymeworks’ suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates.

Zymeworks is seeking a highly motivated professional who is looking to grow their career with our company. In this position, the primary role and focus of the Research Associate I/II will be to develop, qualify and perform ELISA and MSD immunoassays, applied to the characterization of biologics. Experience in the development and application of ELISAs and immunoassays in a pharmaceutical/biotech environment will be particularly useful.

This position will report to the Senior Scientist, Pharmacokinetics and will be based in Vancouver, BC.

As a condition of employment, Zymeworks requires all employees to be fully vaccinated against Covid-19 and provide verification of such.

Key Responsibilities

• Performs routine analysis of biological samples using ELISA, MSD and IP assays with a high degree of reliability, efficiency and accuracy. Develops, troubleshoots, and qualifies more complex bioanalytical methods for the characterization and analysis of biotherapeutics.
• Assists with mammalian cell culture and cell-based assays where needed. Contributes to the design and execution of in-vivo animal studies.
• Documents raw data and performs data analysis. May independently interpret results and present data.
• Completes study reports and maintains adequate experimental records in compliance with company’s standards. Generates high quality methods and study protocols for internal programs. Recommends technical strategies and approaches to meet identified research needs.
• Executes sample management from receiving, to sample organization and archiving, while maintaining satisfactory records throughout the process.
• Assists in oversight of laboratory activities and supports technical staff in the development and execution of studies.
• Implements techniques to improve productivity, increase efficiencies and maintain laboratory state-of-the-art practices.
• Writes operating procedures and other documents, as required.
• Conducts all activities in accordance with scientific standards, OH&S regulations and established policies and practices.
• Fosters effective and collaborative working relationships with fellow employees, management and external partners.

Qualifications and Education

• Requires a BSc in a scientific discipline and a minimum of 2 years’ related experience, or MSc and an equivalent combination of education and experience.
• Experience with characterization and analysis of biotherapeutics (antibodies, FC-fusion proteins and ADCs) using analytical laboratory tools and methodologies, immunoassays in particular would be an asset.
• Demonstrated experience with immunoassay (ELISA, MSD) method development and qualification/validation is preferred.
• Experience with in-vivo animal models would be an asset.
• Experience with mammalian cell culture and cell-based assays would be an asset.
• GLP experience in the core competencies of characterization and analysis of biotherapeutics would be an asset.
• Exceptional analytical and problem-solving capabilities.
• Good organizational skills and the ability to work effectively in a high paced, fast changing environment. Results oriented.
• Effective oral communication and scientific/technical writing skills. Ability to present data at team meetings or interdepartmental meetings.
• Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team. Ability to establish and maintain effective working relationships.
• An equivalent combination of education and experience may be considered.
• Embody and champion Zymeworks’ values: Act with Integrity. Collaborate. Care.
• Adhere to the highest degree of professional standards and strict confidentiality on matters that require discretion.

How to Apply

NOTE TO EMPLOYMENT AGENCIES: Zymeworks values our relationships with our Recruitment Partners. We will only accept resumes from those partners whom have been contracted by a member of our Human Resources team to collaborate with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.

Zymeworks

Zymeworks is an Equal Opportunity Employer

Submitted: 04/30/2022